A Microscopic Study, Mucosal Cells of Urinary Bladder in Streptozotocin Diabetic Rats with Parasite

It has been known that as a result of diabetes several diseases occur in organisms such as parasitic infection. This gives rise to inflammatory conditions associated with mast cells. For the purpose of observing mucosal cells in bladder tissue, streptozotocin diabetic rat bladders were examined with light and electron microscope. A microscopic study of serial sections revealed numerous mast cells in transitional epithelium and lamina propria of bladder mucosa. Mast cells seem to migrate from blood vessels through the transitional epithelium and the lamina propria. Mast cell population found in epithelial layer and lamina propria were observed to differ in characteristics as ultrastructural features. Intraepithelial mast cell cytoplasm were full of granules including both electron dense and lucent material however, mast cells in lamina propria with thin pseudopodia were observed in the process of degranulation. Eosinophil cells beside mast cells were observed in connective tissue of mucosa. These cells were full of electron dense granules in their cytoplasm. Cell interaction between eosinophil and macrophage was evident. Accumulation of mast and eosinophil cells in mucosa and also the cell and tissue interactions could be associated with diabetes and used as a criteria for the evaluation of parasitic (Trichosomoides crassicauda) bladder.